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Feb 10, 21 · Subacute and chronic forms of a sinus infection usually are the result of incomplete treatment of an acute sinus infection Noninfectious sinusitis is caused by irritants and allergic conditions and follows the same general timeline for acute, subacute, and chronic as infectious sinusitisMar 01, 09 · Nasal irrigation and decongestants can help in the treatment of chronic sinusitis by keeping mucus loose and nasal passages clear The mucusthinning agent guaifenesin (Mucinex) is another option (Be sure to drink a full glass of water when you take it) Nasal steroids such as fluticasone (Flonase) or beclomethasone (Beconase) may be added toNasal decongestants work by reducing inflammation and allowing your sinuses to drain Antihistamines work by blocking your body's production of histamines, which cause many sinusitis symptoms Steroids and corticosteroids work by decreasing swelling and inflammation You shouldn't use decongestants for more than a handful of days Tylenol